Help & Support
YourGenome.ai is a new kind of app — one that works with data most people have never been able to access before. If you have a question, we want to answer it.
For questions about your account, subscription, app issues, or anything else. We typically respond within one business day.
support@yourgenome.ai →Questions about how your genomic data is handled, privacy architecture, or your rights under applicable privacy laws.
privacy@yourgenome.ai →Subscription charges and billing are handled directly by Apple. For billing issues, manage your subscription in Settings → Apple ID → Subscriptions.
Apple Billing Support →Supported Genome Formats
Frequently Asked Questions
No. Your raw genome never leaves your device. This is an architectural fact, not just a policy.
When you import your genome file, it is processed entirely on your device. A local SQLite index is built and stored in your app's private storage. All variant lookups, searches, and health reports run against this local index.
The only genomic information that crosses the network is when you use AI Insights: we send gene names and specific genotype calls (e.g., "APOE e2/e3") to generate cross-variant analysis. This is population-level information that cannot identify you as an individual.
See our Privacy Policy for the complete architecture description.
Free tier includes: 23andMe and AncestryDNA import, gene name and rsID search, basic AI interpretation, and search history.
Paid subscription adds: Full VCF whole genome support (millions of variants vs. ~600K chip SNPs), coordinate search, enhanced AI interpretation, auto-updating knowledge base, and polygenic risk scores for conditions including coronary artery disease, type 2 diabetes, Alzheimer's, and cancers.
The auto-updating knowledge base is the primary value of the subscription. Your genome doesn't change — but what science knows about it does. Your subscription keeps you current.
Log in to your 23andMe account at 23andme.com. Go to Settings (top right menu) → 23andMe Data → Download Raw Data.
You'll receive a .zip file containing a .txt file — that's your genome file. Import it directly into YourGenome.ai; we'll handle the rest.
If you're having difficulty with the 23andMe export process, 23andMe's own support is the best resource: customercare.23andme.com
A polygenic risk score (PRS) estimates your genetic predisposition to a condition based on hundreds of thousands of genetic variants across your genome — not just single variants, but patterns that together indicate risk.
YourGenome.ai includes PRS for coronary artery disease, type 2 diabetes, Alzheimer's disease, prostate cancer, and breast cancer. Each score is expressed as a percentile — your genetic risk compared to the general population.
Important: Polygenic risk scores reflect genetic predisposition, not destiny. They are one input among many — lifestyle, environment, and other factors matter enormously. A high PRS means higher relative risk, not a diagnosis. A low PRS does not mean you are protected.
Always discuss genetic risk information with a qualified healthcare provider before making medical decisions.
The YourGenome.ai knowledge base contains 440+ manually curated variants with references to published scientific literature. We review sources carefully and flag the strength of evidence for each finding.
A few important caveats:
Chip-based tests (23andMe, AncestryDNA) genotype ~600K positions across your genome. If a clinically important variant isn't on the chip, it won't appear in your results. This includes some BRCA1/2 variants — chip results for these should always be confirmed by clinical sequencing before acting on them.
Whole genome VCF files cover ~4-5 million variant positions and are more comprehensive, but even whole genome sequencing has limitations for certain structural variants and repetitive regions.
YourGenome.ai is an informational tool. It is not a medical device and does not provide medical diagnoses. Discuss any findings with a healthcare provider or genetic counselor.
If you enable iCloud sync, your processed genome index (not the raw genome file) syncs between your iPhone and Mac via iCloud Drive. This means you only need to import your genome file once — the searchable index travels between your devices automatically.
The sync uses Apple's iCloud infrastructure. We don't have access to the synced data — it moves directly between your devices under your Apple ID.
You can disable sync at any time in your device's Settings → [Your Name] → iCloud → YourGenome.ai.
Subscriptions are managed through Apple. To cancel:
On iPhone: Settings → [Your Name] → Subscriptions → YourGenome.ai → Cancel Subscription.
On Mac: App Store → [Your Name] → Manage → Subscriptions → YourGenome.ai → Cancel.
Your subscription remains active through the end of the current billing period. Canceling removes access to paid features at renewal — your locally stored genome data is never affected.
If you find a variant or risk score that concerns you, the right next step is to speak with a healthcare provider or a board-certified genetic counselor. They can help you understand what the finding means in the context of your personal and family history, and what — if any — follow-up is appropriate.
Finding Your Genetics resources: The National Society of Genetic Counselors (findageneticcounselor.nsgc.org) maintains a searchable directory of genetic counselors.
YourGenome.ai is designed to inform curiosity, not cause alarm. Most variants — even those flagged as "elevated risk" — represent modest increases in relative risk, not certainties. Context is everything.